
Comprehensive Dermal Filler Overview
1. Allergan Aesthetics, an AbbVie Company
CosmoDerm
– Key Component: Purified human-based collagen (35 mg/mL)
– Description:
– Purified collagen product
– All collagen products contain 0.3% lidocaine
CosmoPlast
– Key Component: Purified human-based collagen (35 mg/mL), cross-linked with glutaraldehyde
– Description:
– Includes 0.3% lidocaine
– Aimed at soft-tissue augmentation
HydraFill – Softline / Softline Max
– Key Component:
Non-animal hyaluronic acid
– Description:
– Cross-linked cohesive HA (24 mg/g)
– Used to correct moderate to severe facial lines and folds
Juvéderm ULTRA 2
– Key Component:
Non-animal hyaluronic acid
– Description:
– Cross-linked cohesive HA (24 mg/g) + lidocaine
– For superficial to mid-dermal injections
Juvéderm ULTRA 3
– Key Component:
Non-animal hyaluronic acid
– Description:
– Cross-linked cohesive HA (24 mg/g)
– Intended for mid-to-deep dermal injections to correct moderate wrinkles
Juvéderm ULTRA 4
– Key Component:
Non-animal hyaluronic acid
– Description:
– Cross-linked cohesive HA (24 mg/g)
– For deeper dermal injections to address prominent folds and wrinkles
Juvéderm VOLITE
– Key Component:
Non-animal hyaluronic acid
– Description:
– Cross-linked cohesive HA (20 mg/g)
– Improves skin quality, including hydration, elasticity, and smoothness
Juvéderm HYDRATE
– Key Component: Hyaluronic acid (13.5 mg/g) plus mannitol (0.9%)
– Description:
– Often injected superficially to improve skin hydration, radiance, and elasticity
JUVÉDERM VOLUMA XC
– Key Component: Hyaluronic acid
– Description:
– For subcutaneous or deeper supraperiosteal injection
– Restores midface and cheek volume, providing lift and contour
JUVÉDERM VOLUX XC
– Key Component: Hyaluronic acid
– Description:
– Designed for deeper injections into the jawline and chin area
– Used for enhanced definition and a more sculpted lower face
JUVÉDERM VOLBELLA XC
– Key Component: Hyaluronic acid
– Description:
– Treats vertical lip lines
– Adds subtle volume to the lips
JUVÉDERM Ultra XC
-Key Component: Hyaluronic acid
– Description:
– Injectable gel for mid-to-deep injection to correct moderate to severe wrinkles and folds
– Also used for lip augmentation
JUVÉDERM Ultra Plus XC
– Key Component: Hyaluronic acid
– Description:
– For mid-to-deep dermal injections to address moderate to severe wrinkles, such as nasolabial folds
—
2. Galderma Laboratories, L.P.
Restylane-L
– Key Component: Hyaluronic acid (NASHA™ Technology)
– Description:
– Mid-to-deep injection for moderate to severe facial wrinkles and folds
– Also indicated for lip augmentation
Restylane Lyft
– Key Component: Hyaluronic acid (NASHA™ Technology)
– Description:
– Deep dermis to superficial subcutis injection
– Treats midface volume deficiencies and wrinkles such as nasolabial folds
– Used for cheek augmentation
Restylane Silk
– Key Component: Hyaluronic acid (NASHA™ Technology)
– Description:
– Lip augmentation and superficial dermal implantation
– Corrects perioral rhytids
Restylane Contour
– Key Component: Hyaluronic acid (XpresHAn Technology™)
– Description:
– Cheek augmentation
– Correction of midface contour deficiencies
Restylane Defyne
– Key Component: Hyaluronic acid (XpresHAn Technology™)
– Description:
– Addresses moderate to deep smile and laugh lines (nasolabial folds, marionette lines)
– Helps preserve natural facial expressions
Restylane Kysse
– Key Component: Hyaluronic acid (XpresHAn Technology™)
-Description:
– Adds volume and softness to the lips
Restylane Refyne
– Key Component: Hyaluronic acid (XpresHAn Technology™)
– Description:
– Designed for natural results in moderate to severe facial wrinkles and folds
– Maintains facial flexibility
Sculptra
– Key Component: Injectable poly-L-lactic acid
– Description:
– Corrects shallow to deep nasolabial folds, contour deficiencies, and other wrinkles
– Often used for patients experiencing lipoatrophy
—
3. Merz Aesthetics
Belotero Balance – 22.5 mg/mL
– Key Component: Hyaluronic acid
– Description:
– Sterile, bioresorbable, non-pyrogenic, viscoelastic, and clear gel
– Injected to smooth moderate-to-severe facial wrinkles and folds
Radiesse
– Key Component:
Calcium Hydroxyapatite (CaHA)
– Description:
– Sterile, non-pyrogenic, semi-solid, cohesive implant
– Synthetic calcium hydroxyapatite in a gel carrier
– Adds structural support and corrects deeper lines
Radiesse (+)
– Key Component: Calcium Hydroxyapatite (CaHA) with Lidocaine
– Description:
– Similar to Radiesse, but includes lidocaine to reduce treatment discomfort
—
4. MTF Biologics
Renuva
– Key Component: Allograft Adipose Matrix
– Description:
– Derived from donated allograft adipose extracellular matrix
– Contains collagen, growth factors, and proteins found in natural adipose tissue
—
5. Prollenium Medical Technologies, Inc.
Revanesse Versa
– Key Component: Hyaluronic acid filler
– Description:
– Treats moderate to severe facial wrinkles and folds (e.g., nasolabial folds)
– Known for smooth consistency and natural-looking results
Revanesse Lips
– Key Component: Hyaluronic acid filler
– Description:
– Specifically formulated for lip augmentation
– Typically for patients 22 years of age or older
—
6. Revance
RHA Redensity (RHA 2)
– Key Component: Preserved Network Technology non-animal Hyaluronic Acid (15 mg/mL) + Lidocaine (0.3%)
– Description:
– Addresses moderate to severe perioral rhytids (lip lines)
– Low stretch score and high dynamic strength
RHA 3
– Key Component: Preserved Network Technology non-animal Hyaluronic Acid (23 mg/mL) + Lidocaine (0.3%)
– Description:
– Injected into the mid-to-deep dermis for moderate to severe dynamic wrinkles and folds (e.g., nasolabial folds)
RHA 4
– Key Component: Preserved Network Technology non-animal Hyaluronic Acid (23 mg/mL) + Lidocaine (0.3%)
– Description:
– For deep dermis to superficial subcutaneous injections
– Corrects moderate to severe dynamic wrinkles and folds
—
References
1. Dermal Filler Product Comparison Chart – Allergan Aesthetics, an AbbVie Company
2. Dermal Filler Product Comparison Chart – Galderma Laboratories, L.P.
3. Dermal Filler Product Comparison Chart – Merz Aesthetics
4. Dermal Filler Product Comparison Chart – MTF Biologics
5. Dermal Filler Product Comparison Chart – Prollenium Medical Technologies, Inc.
6. Dermal Filler Product Comparison Chart – Revance